Control is a third-person action-adventure game set in the Federal Bureau of Control, a secretive U. S. government agency that studies paranormal phenomena. Players control Jesse Faden, who arrives at the Bureau's headquarters, the Oldest House, to find it invaded by a hostile force called the Hiss. Gameplay combines supernatural abilities with a shape-shifting firearm, and the environment is reactive and destructible.

After a secretive agency in New York is invaded by an otherworldly threat, you become the new Director struggling to regain Control. Control is Jesse Faden’s story and her personal search for answers as she grows into the role of the Director. The world of Control has its own story, as do the allies Jesse meets along the way. Jesse works with other Bureau agents and discovers strange experiments and secrets.