In Kimagure Strawberry Cafe you play as Ichigo Mizuhara (default name) and your luck left you when your parents suddenly decide to have a trip for a whole year. Things couldn't get any worse, now you are in charge of a cafe that your parents left you. Well things aren't so bad when you have a childhood friend and your cute underclassmen to help you run the cafe. And who say lady luck just left you, when now suddenly you are stranded to manage the cafe with 5 cute guys.

A dream trip around the world! ...Is a trip the protagonist, Mizuhara Ichigo's parents are taking without her. She's busy in her 3rd year of high school and preparing for graduation and university entrance exams. She wants to fall in love too, what should she do? She wants to play around, but she's too serious at her core, so she asks her friends for advice but all they can say is that she has some bad luck. Taking a year long trip and leaving their daughter in charge of the café they run, how selfish of her parents. The shop is important to her too, but what about their cute only daughters precious youth. Now for the next year she has to take care of the cafe, still go to school, and prepare for university. Even more she wants to just once in her youth live like a maiden in love. Where are those guys that should be watching over her in this town? A love cafe simulation game with bittersweet guys.