Digimon Story: Cyber Sleuth – Hacker's Memory is a role-playing game, played from a third-person perspective where the player takes control of Keisuke Amasawa, a Digimon tamer who can command up to three of his companions in battle against other Digimon. It features 341 creatures in total, including all those present in the original version of Digimon Story: Cyber Sleuth, plus an additional 92.

"Set in the near future, the line between the real and digital worlds is blurred and logging into cyberspace is a part of everyday life. In the shadows lurk hackers utilizing computer viruses called Digimon to commit mischief and crimes. Framed and accused of wrongdoings, Keisuke Amazawa has no choice but to dive into the digital world to not only clear his name and prove his innocence, but to protect his loved ones."