Atomine is a twin stick procedural shooter rogue-lite set in a virtual world with minimalist design, where the player recounts on the screen the real events of Stuxnet, the first weapon ever created in the form of computer virus. In every run the player has to clear the level area from all the enemies in order to unlock the portal to the next level. During the run every killed enemy will leave on the ground XPs, energy and/or weapon modules.

In 2011, Sergey Ulasen, discovered STUXNET, a malicious computer worm, initially spreaded via Microsoft Windows, and targeted Siemens industrial control systems, defined as a sleeping threat, waiting for a trigger to start its activation. STUXNET is the first discovered malware that spies on and subverts industrial systems, and the first to include a programmable logic controller (PLC) rootkit. The worm has been founded infecting especially nuclear power plants and oil drilling systems. ATOMINE, like STUXNET, is a virus who needs to get stronger in order to reach and eventually infect and compile itself into the target source code. The electronic voice in the background and many element on screen, tell to the player what's the target of the run.