Digital Devil Story: Megami Tensei II is the sequel to Digital Devil Story: Megami Tensei. It was published by Namco in 1990 for the Family Computer and is the second video game in the Megami Tensei series. This is the first game in the series to not be based on the original novels by Aya Nishitani, but it retains much of the gameplay aspects of its predecessor. The music in the game is enhanced by an eight-channel Namco 163 WSG sound chip on the cartridge.

In the year 199X, the world was demolished with a bombardment of missiles, and the survivors of the cataclysm were forced to live in shelters. It's now the year 2036, and two friends are playing a video game called 'Devil Busters' in the Keihin shelter No. 3. Shortly after they beat the first boss, they unseal Pazuzu. The demon gives them the Demon Summoning Program in hopes of using it for the defeat of Bael along with a warning of a coming menace. Demons then begin to raid the shelter and the two friends must save the remains of humanity.